miRNA-Dependent Activation of mRNA Translation

Author(s): Wen-Juan Ni , Xiao-Min Leng .

Journal Name: MicroRNA

Volume 5 , Issue 2 , 2016

Become EABM
Become Reviewer

Graphical Abstract:


Abstract:

MicroRNAs (miRNAs) are small and important RNA molecules. They can regulate gene expression at different levels. Although their biogenesis has been well documented, elucidation of miRNA-dependent activation of mRNA translation has just begun. Here, we highlighted different patterns of miRNA-dependent activation of mRNA translation: miRNA can activate mRNA translation through binding different target sites; in different sub-cellular locations; under different cellular circumstances. MiRNA-dependent activation of mRNA translation suggests unexpected functions of miRNA, that could provide new clues in functional studies of other ncRNAs.

Keywords: Cellular circumstance, gene expression, miRNA, sub-cellular location, target site, translational activation.

Rights & PermissionsPrintExport Cite as

Article Details

VOLUME: 5
ISSUE: 2
Year: 2016
Page: [83 - 86]
Pages: 4
DOI: 10.2174/2211536605666160825151201
Price: $58

Article Metrics

PDF: 27
HTML: 5