Type 2 Diabetes Mellitus (T2DM) and its complications are more prevalent in the elderly. As
the general population worldwide is ageing, effective and safe treatment of older T2DM patients is becoming
more important in clinical practice. Elderly T2DM patients should be carefully evaluated for
functional, mental, geriatric and medical disorders before the initiation of antidiabetic drug therapy and
regularly monitored thereafter. Treatment strategy and goals should be individualized based on patient comorbidities
and drug pharmacokinetic and pharmacodynamic properties. This narrative review discusses
the use of antidiabetic drugs in the elderly T2DM population.
Keywords: Elderly, type 2 diabetes mellitus, antidiabetic drugs, kidney dysfunction, diabetic complications.
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