Recent advances in the treatment of cerebral gliomas have increased the demand for
diagnosis by means of neuroimaging in order to assist in treatment planning and prognosis. Advanced
magnetic resonance (MR) imaging techniques, including MR spectroscopy (MRS) and
MR perfusion, have proved invaluable in evaluating key pathological features of gliomas. MRS
provides a broad range of information about cell membrane proliferation, neuronal integrity,
energy metabolism, and necrosis of tumor tissue, while perfusion MR imaging provides valuable
information about tumor neoangiogenesis. Together these imaging techniques aid in the
grading of a glioma, a necessary step before planning a course of treatment. This report provides
an up-to-date review of brain MRS and MR perfusion techniques and discusses their potential
roles in glioma grading.
Keywords: Brain, glioma, grade, magnetic resonance imaging, magnetic resonance perfusion, magnetic resonance spectroscopy.
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