Natural products are widely found in nature, their number and variety are numerous, the
structures are complex and diverse. These natural products have many physiological and
pharmacological activities. Glycosylation can increase the diversity of structure and function of natural
product, it has become the focus of drug research and development. The impacts of glycosylation of
natural products to water solubility, pharmacological activities, bioavailability, or others were
described in this review, which provides a reference for the development and application of
glycosylated natural products.