Introduction: Development of new and improved mosquito control
methods, that are economically sustainable and effective, is a critical requirement in
the management of vector-borne epidemic diseases. Aedes albopictus is one of the
main vectors of various important pathogens in the tropics, which now have the
potential to also spread in temperate regions, owing to the environmental and climate
changes in act.
Materials and Methods: We report about the isolation of steroidal saponins from
Dracaena arborea by fractionation followed by column separation. The obtained
fractions and/or pure compounds were tested by biological essays for their insecticidal
activity against A. albopictus larvae.
Results: Various compounds were found to exert larvicidal effects. In specific, spiroconazole A demonstrated
the best insecticidal activity, showing LT50 value of 57.23 hours at 25 ppm.
Discussion: We finally discuss about the value of this finding in the context of the present strategies of
Integrated Mosquito Management.