Abstract
Gentiopicroside is a secoiridoid compound isolated from Gentiana lutea which is called Qin Jiao in Chinese. It is one of the most common herbal medicines used in China. In this article, we review the pharmacological and biological activity (antiviral, anti-inflammatory, analgesia, antihepatotoxic and choleretic), as well as biotransformation of the gentiopicroside. In addition, attempt towards the total synthesis of gentiopicroside is also presented.
Keywords: Biological activity, biotransformation, gentiopicroside, natural product, secoiridoid, total synthesis.
Mini-Reviews in Medicinal Chemistry
Title:Research Progress of Natural Product Gentiopicroside - a Secoiridoid Compound
Volume: 17 Issue: 1
Author(s): Shaoping Wu, Yaoyao Ning, Yingyong Zhao, Wenji Sun, Serge Thorimbert, Luc Dechoux, Matthieu Sollogoub and Yongmin Zhang
Affiliation:
Keywords: Biological activity, biotransformation, gentiopicroside, natural product, secoiridoid, total synthesis.
Abstract: Gentiopicroside is a secoiridoid compound isolated from Gentiana lutea which is called Qin Jiao in Chinese. It is one of the most common herbal medicines used in China. In this article, we review the pharmacological and biological activity (antiviral, anti-inflammatory, analgesia, antihepatotoxic and choleretic), as well as biotransformation of the gentiopicroside. In addition, attempt towards the total synthesis of gentiopicroside is also presented.
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Cite this article as:
Wu Shaoping, Ning Yaoyao, Zhao Yingyong, Sun Wenji, Thorimbert Serge, Dechoux Luc, Sollogoub Matthieu and Zhang Yongmin, Research Progress of Natural Product Gentiopicroside - a Secoiridoid Compound, Mini-Reviews in Medicinal Chemistry 2017; 17 (1) . https://dx.doi.org/10.2174/1389557516666160624124127
DOI https://dx.doi.org/10.2174/1389557516666160624124127 |
Print ISSN 1389-5575 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5607 |
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