An Efficient Synthesis of 1,2-Oxazine Derivatives via the Reaction of Acetylenic Esters and 1,2-Diketone Monoxime Derivatives in the Presence of Ph3P

Author(s): Mitra Saghafi, Razieh Mohebat.

Journal Name: Letters in Organic Chemistry

Volume 13 , Issue 6 , 2016

Become EABM
Become Reviewer

Graphical Abstract:


Abstract:

The reactive 1:1 intermediate obtained by the addition of triphenylphosphine to dialkyl acetylenedicarboxylates was trapped by 1,2-diketone monoximes to generate functionalized 1,2-oxazine derivatives through intramolecular Wittig reaction without any catalyst in excellent yields.

Keywords: 1, 2-Diketone monoxime, Triphenylphosphine, Acetylenic esters, 1, 2-Oxazine, Intramolecular Wittig reaction.

Rights & PermissionsPrintExport Cite as


Article Details

VOLUME: 13
ISSUE: 6
Year: 2016
Page: [437 - 440]
Pages: 4
DOI: 10.2174/1570178613666160624114703
Price: $58

Article Metrics

PDF: 15
HTML: 2
EPUB: 1
PRC: 1