Heterocyclic compounds are a class of substances, which play a critical role in
modern drug discovery being incorporated in the structure of a large variety of drugs used in
many different types of diseases. Quinoxaline is an important heterocyclic nucleus with a wide
spectrum of biological activities, and recently much attention has been found on anticancer drug
discovery based on this class. Owing to the importance of this system, the aim of this review is
to provide an update on the synthesis and anticancer activity of quinoxaline derivatives covering
articles published between 2010 and 2015.
Keywords: Cancer, drug discovery, synthesis, quinoxaline, heterocyclic compounds, biological activity.
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