A novel series of novel 1,2,4-triazolo[4,3-a]pyridines were designed and synthesized under
microwave irradiation condition. The structures were identified by 1H NMR, MS and elemental
analysis, and the antifungal activities of them were evaluated at 100 ppm. It was found that some of
the 1,2,4-triazolo[4,3-a]pyridines displayed good antifungal activity. Among them, compound 2e exhibited
good antifungal activity against Stemphylium lycopersici (Enjoji) Yamamoto and Fusarium
oxysporum. Sp. Cucumebrium.
Keywords: 1, 2, 4-triazolo[4, 3-a]pyridine, antifungal activities, microwave assisted synthesis, thioether.
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