Tissue engineering has emerged as a promising scientific field potentially
yielding in vitro developed tissue to replace degenerative or injured tissues in vivo,
thus avoiding the donor site morbidity associated with reconstructive surgery. Integral
to the process is the role of scaffolds and the biomaterials used to form them. This
review explores the concept of scaffold based tissue engineering and design considerations.
The scaffold needs to have certain mechanical and architectural properties, it
needs to be biocompatible and biodegradable, and allow combination with bioactive
molecules. We also discuss scaffolding techniques, different biomaterial options and
fabrication technologies, and future areas of development.
Keywords: Biomaterials, bioreactors, fabrication, scaffolds, tissue engineering.
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