Abstract
Tissue engineering has emerged as a promising scientific field potentially yielding in vitro developed tissue to replace degenerative or injured tissues in vivo, thus avoiding the donor site morbidity associated with reconstructive surgery. Integral to the process is the role of scaffolds and the biomaterials used to form them. This review explores the concept of scaffold based tissue engineering and design considerations. The scaffold needs to have certain mechanical and architectural properties, it needs to be biocompatible and biodegradable, and allow combination with bioactive molecules. We also discuss scaffolding techniques, different biomaterial options and fabrication technologies, and future areas of development.
Keywords: Biomaterials, bioreactors, fabrication, scaffolds, tissue engineering.
Current Stem Cell Research & Therapy
Title:Biomaterials and Fabrication to Optimise Scaffold Properties for Musculoskeletal Tissue Engineering
Volume: 11 Issue: 7
Author(s): Andrew Wheelton, James Mace, Wasim S. Khan and Sanjay Anand
Affiliation:
Keywords: Biomaterials, bioreactors, fabrication, scaffolds, tissue engineering.
Abstract: Tissue engineering has emerged as a promising scientific field potentially yielding in vitro developed tissue to replace degenerative or injured tissues in vivo, thus avoiding the donor site morbidity associated with reconstructive surgery. Integral to the process is the role of scaffolds and the biomaterials used to form them. This review explores the concept of scaffold based tissue engineering and design considerations. The scaffold needs to have certain mechanical and architectural properties, it needs to be biocompatible and biodegradable, and allow combination with bioactive molecules. We also discuss scaffolding techniques, different biomaterial options and fabrication technologies, and future areas of development.
Export Options
About this article
Cite this article as:
Wheelton Andrew, Mace James, Khan S. Wasim and Anand Sanjay, Biomaterials and Fabrication to Optimise Scaffold Properties for Musculoskeletal Tissue Engineering, Current Stem Cell Research & Therapy 2016; 11 (7) . https://dx.doi.org/10.2174/1574888X11666160614101037
DOI https://dx.doi.org/10.2174/1574888X11666160614101037 |
Print ISSN 1574-888X |
Publisher Name Bentham Science Publisher |
Online ISSN 2212-3946 |
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
- Announcements
Related Articles
-
Multimodality Imaging for Interventional Cardiology
Current Pharmaceutical Design Hyaluronan and Hyaluronan Synthases: Potential Therapeutic Targets in Cancer
Current Drug Targets - Cardiovascular & Hematological Disorders Abdominal Aortic Aneurysm: What About Screening?
Current Pharmaceutical Design Inflammatory Cells and Chronic Obstructive Pulmonary Disease
Current Drug Targets - Inflammation & Allergy Antiphospholipid Syndrome as a Neurological Disease
Current Rheumatology Reviews Strategies for Antimicrobial Drug Delivery to Biofilm
Current Pharmaceutical Design Apolipoprotein E Knockout Models
Current Pharmaceutical Design Multifaceted Synthesis, Properties and Applications of Polyurethanes and its Composites
Current Organic Chemistry Home Oxygen Therapy for the 21st Century
Current Respiratory Medicine Reviews Synthetic Sustained Gene Delivery Systems
Current Topics in Medicinal Chemistry Preoperative Levosimendan. A New Way for Organoprotection
Current Pharmaceutical Design Proteome and Metabolome Alterations in Heart and Liver Indicate Compromised Energy Production During Sepsis
Protein & Peptide Letters Diagnostic Value of Postprandial Triglyceride Testing in Healthy Subjects:A Meta-Analysis
Current Vascular Pharmacology Fractal Analysis of the Bone Marrow in Myelodysplastic Syndromes
Current Bioinformatics Type 1 Diabetes Mellitus - Risk Factor for Cardiovascular Disease Morbidity and Mortality
Current Diabetes Reviews Novel Therapeutic Strategies for the Homozygous Familial Hypercholesterolemia
Recent Patents on Cardiovascular Drug Discovery A Unique Intracellular, Extracellular and Transmembrane Circulation of Potassium Ions in the Auditory Inner Ear as an Anticarcinogenic Principle? Part 1
Inflammation & Allergy - Drug Targets (Discontinued) Assessing Systemic Arterial Hypertension Through Echocardiography: A Review for the Clinician
Current Hypertension Reviews The Multiple Electrocardiographic Manifestations of Ventricular Repolarization Memory
Current Cardiology Reviews Targeting Potassium Channels: New Advances in Cardiovascular Therapy
Recent Patents on Cardiovascular Drug Discovery