Biomaterials and Fabrication to Optimise Scaffold Properties for Musculoskeletal Tissue Engineering

Author(s): Andrew Wheelton , James Mace , Wasim S. Khan , Sanjay Anand .

Journal Name: Current Stem Cell Research & Therapy

Volume 11 , Issue 7 , 2016

Become EABM
Become Reviewer

Abstract:

Tissue engineering has emerged as a promising scientific field potentially yielding in vitro developed tissue to replace degenerative or injured tissues in vivo, thus avoiding the donor site morbidity associated with reconstructive surgery. Integral to the process is the role of scaffolds and the biomaterials used to form them. This review explores the concept of scaffold based tissue engineering and design considerations. The scaffold needs to have certain mechanical and architectural properties, it needs to be biocompatible and biodegradable, and allow combination with bioactive molecules. We also discuss scaffolding techniques, different biomaterial options and fabrication technologies, and future areas of development.

Keywords: Biomaterials, bioreactors, fabrication, scaffolds, tissue engineering.

Rights & PermissionsPrintExport Cite as

Article Details

VOLUME: 11
ISSUE: 7
Year: 2016
Page: [578 - 584]
Pages: 7
DOI: 10.2174/1574888X11666160614101037
Price: $58

Article Metrics

PDF: 16
HTML: 2
EPUB: 1
PRC: 1