This review highlights recent advances in the preparation of silica nanoparticles
(SNPs) functionalized with porphyrins and phthalocyanines for application in cancer photodiagnostic
and photodynamic therapy (PDT). The use of photosensitizer-SNP formulations
has emerged recently as a new nanomedicine for cancer research owing to their unique physicochemical
properties, which make them useful for photo-biomedical applications. In order
to study their photobiological properties, diverse chemical strategies involving covalent and
non-covalent bonding have been used to load photosensitizers in/on SNPs.
Keywords: Porphyrins, Phthalocyanines, Photosensitizers, Silica Nanoparticles, PDT, Cancer.
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