Transition Metal-free Photoorganocatalytic Fluoroalkylation Reactions of Organic Compounds

Author(s): Sebastián Barata-Vallejo , Damian E. Yerien , Beatriz Lantano , Al Postigo .

Journal Name: Current Organic Chemistry

Volume 20 , Issue 27 , 2016

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Abstract:

The generation of perfluoroalkyl radicals (RF•) by means of photocatalysis is a more suitable route than the established methods employing chemical initiators, like azo or peroxide compounds or the use of transition metals. Conditions governed by photocatalysis can allow for a wide range of functional groups and, therefore, can be applied to the latestage transformation of bioactive molecules. Organic photocatalysts (POC), in the absence of transition metals, can suffer electron-exchange reactions, yielding RF radicals. RF radical production without the assistance of transition metals through the employment of POC will be described, applying this methodology to studying classical examples.

Keywords: Photo-organocatalysis, fluoroalkyl radicals, organic dyes.

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Article Details

VOLUME: 20
ISSUE: 27
Year: 2016
Page: [2838 - 2847]
Pages: 10
DOI: 10.2174/1385272820666160614080432
Price: $58

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