The Chemistry and Bio-Medicinal Significance of Pyrimidines & Condensed Pyrimidines

Author(s): K. S. Jain, N. Arya, N. N. Inamdar, P. B. Auti, S. A. Unawane, H. H. Puranik, M. S. Sanap, A. D. Inamke, V. J. Mahale, C. S. Prajapati, C. J. Shishoo.

Journal Name: Current Topics in Medicinal Chemistry

Volume 16 , Issue 28 , 2016

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Abstract:

This review discusses the biological and medicinal significance of one of the most important and interesting heterocyclic ring systems, the pyrimidine and its condensed derivatives. Herein, various physiologically important molecules, as well as, therapeutically used drugs having a pyrimidine or condensed pyrimidine system in their chemical structures, have been covered. The chemistry and synthesis of pyrimidines have also been briefly discussed.

Keywords: Bioactive Heterocycles, Pyrimidines, Condensed Pyrimidines, Biological significance, Medicinal significance, Synthesis.

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Article Details

VOLUME: 16
ISSUE: 28
Year: 2016
Page: [3133 - 3174]
Pages: 42
DOI: 10.2174/1568026616666160609100410
Price: $58

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