Pressure sores are a major complication in the bed-ridden older patient. In this report, we present
the case of platelet rich plasma (PRP) application for the treatment of a pressure sore in an 88-year-old
female affected by transfusion-dependent chronic inflammatory disease anemia associated with the congenital
and inherited condition of thalassemic trait carrier. A weekly application schedule was planned athome,
given the patient’s debilitation and her decreased performance status as well as personal and family
difficulties to go as outpatients at our treatment center. After 9 PRP applications, a remarkable sore improvement
was achieved so that PRP was discontinued; nevertheless, sore rapidly improved until the full
resolution and the complete closing after 4 months from the start of PRP treatment. Noteworthy, transfusion
support was interrupted and a significant recovery and a sustained stabilization of hemoglobin (Hb) level
at 1 year after ulcer healing were observed. The present case suggests that PRP application, performed athome
in our case, is a feasible and effective treatment for pressure sores and related complications.
Keywords: Anemia, autologous patient, home care, platelet rich plasma (PRP), pressure sore, thalassemia trait carrier.
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