Benzothiazole Derivatives as Potential Anti-Infective Agents

Author(s): Prabodh Chander Sharma, Kushal Kumar Bansal, Aakash Deep, Meenakshi Pathak.

Journal Name: Current Topics in Medicinal Chemistry

Volume 17 , Issue 2 , 2017

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Abstract:

Background: Severity of microbial infections and escalating resistance towards antibiotics has created a deep necessity for discovery of novel anti-infective agents. Heterocyclic chemistry of benzothiazole has become one of the most prolific areas in the field of drug discovery and development that has attracted great attention in recent time due to its increasing importance in the field of pharmaceuticals.

Method: The importance of benzothiazole and derivatives as potential antimicrobial agents has been well established and a large number of papers have been published in this regard.

Result: The present communication is an earnest attempt to review the chemistry, synthetic aspects including click chemistry and antimicrobial activities of benzothiazole derivatives reported in recent scientific literature.

Conclusion: The scientific information of this manuscript may be worthwhile in encouraging the prospective researchers working on this heterocyclic scaffold.

Keywords: Benzothiazole, Synthesis, Click Chemistry, Anti-infective activity, Chemotherapy.

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Article Details

VOLUME: 17
ISSUE: 2
Year: 2017
Page: [208 - 237]
Pages: 30
DOI: 10.2174/1568026616666160530152546
Price: $58

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