Title:Ionic Liquid in Multicomponent Reactions: A Brief Review
VOLUME: 3 ISSUE: 2
Author(s):Lennine R. Melo and Wender A. Silva
Affiliation:Laboratory for Bioactive Compound Synthesis, University of Brasilia (IQ-UnB). Campus Universitario Darcy Ribeiro, CEP 70904970, P.O.Box 4478, Brasilia-DF, Brazil.
Keywords:Environment, ionic liquid, multicomponent reactions, sustainable.
Abstract:Chemistry today is focused on the development of most effective reactions
and methodologies that should be used in more sustainable and eco-friendly
conditions. The ionic liquids are recognized for their ability to form clusters and
enhance properties of certain catalysts. Attempts to connect the advantages of catalysis
in ionic liquids (IL) with multicomponent reaction (MCR) are found. Multicomponent
Reactions (MCRs) offer many advantages, and due to there ability to
quickly create molecular diversity and molecular complexity allowing the generation
of compounds containing essentially all atoms of reactants, they have become
an important new way of synthesizing bioactive products.
Methods: The main results reported from 2012 until the present day are summarized
in this review about catalysis in ionic liquids (IL) with multicomponent reaction (MCR).
Results: Several research groups are highlighted in catalysis study in ionic liquids to further enhance
the results of possibilities within the universe of multicomponent reactions, showing his versatility in
synthesizing complex systems with high convergence and good yields.
Conclusion: A wide range of multicomponent reaction in ionic liquid showed in this review confirms
that this area of science stands out for presenting general methods and mild and environmentally
friendly conditions.
