Cannabis for Refractory Psoriasis—High Hopes for a Novel Treatment and a Literature Review

Author(s): Nima Derakhshan, Mahboubeh Kazemi.

Journal Name: Current Clinical Pharmacology

Volume 11 , Issue 2 , 2016

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Abstract:

Psoriasis is a common skin disorder characterized by hyper proliferation of keratinocytes. Although the exact pathophysiology of psoriasis is not entirely understood, immune system and its interaction with nervous system have been postulated and investigated as the underlying mechanism. The interaction between these two systems through cholinergic anti-inflammatory pathway and also endocannabinoid system, may suggest cannabinoids as potential addition to antipsoriatic armamentarium.

Keywords: Psoriasis, immunomodulation, cannabidiol, endocannabinoids, vagal nerve stimulation.

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Article Details

VOLUME: 11
ISSUE: 2
Year: 2016
Page: [146 - 147]
Pages: 2
DOI: 10.2174/1574884711666160511150126
Price: $58

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