Cancer is a serious hazard to human health all around the world; however, many current therapies remain
toxic and poor. In view of the understanding of immunology and tumor biology, cancer immunotherapy
with minimal toxicity has been regarded as a promising strategy for cancer treatment because of immune surveillance.
Unfortunately, the efficacy of immunotherapy was impeded and resisted due to the tumor immune evasion
mechanism. Hence, targeted cancer immunotherapy has been proposed to tackle the tumor immune suppression
and complexity of malignant tumor cells. Nanotechnology-based immunotherapy has improved the limitations
and enhanced the therapeutic efficiency of traditional immunotherapy. This review illustrates the recent progresses
in immunotherapy based on nanotechnology, and reveals that nanodevices could be utilized for active and
passive cancer immunotherapy.
Keywords: Cancer, immunotherapy, tumor immune surveillance, escape mechanism, nanotechnology, drug delivery.
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