Abstract
Background: Due to the continuing increase of the elderly population in the western countries, the prevalence of the main chronic diseases (obesity, type 2 diabetes and related metabolic disorders, arterial hypertension, vascular damage due to atherosclerotic process, cancer, chronic obstructive pulmonary disease, neurodegenerative diseases, chronic kidney disease, immune-mediated diseases) is increasing. There is incontrovertible evidence that regular physical activity contributes to the primary and secondary prevention of several chronic diseases and is associated with a reduced risk of premature death.
Methods: In this review the most prevalent chronic pathologic conditions are discussed, how regular exercise may provide benefits for prevention and/or treatment of these diseases and are graphically described by means of various figures the main biological mechanisms through which exercise exerts its beneficial effects known to date.
Results: Specific interventions aimed to implement physical activity levels of the general population are of certain efficacy both for primary and secondary prevention of the major chronic diseases and constitutes an excellent cost/effective tool to improve the health status of different categories of patients.
Conclusion: Exercise represents a unique case in which a single intervention is useful against a broad range of diseases and risk factors, this knowledge should lead to an ever-increasing use of this lifestyle change.
Keywords: Regular exercise, chronic diseases, primary prevention, secondary prevention.
Current Pharmaceutical Design
Title:Preventive and Therapeutic Role of Muscle Contraction Against Chronic Diseases
Volume: 22 Issue: 30
Author(s): Domenico Di Raimondo, Gaia Musiari, Giuseppe Miceli, Valentina Arnao and Antonio Pinto
Affiliation:
Keywords: Regular exercise, chronic diseases, primary prevention, secondary prevention.
Abstract: Background: Due to the continuing increase of the elderly population in the western countries, the prevalence of the main chronic diseases (obesity, type 2 diabetes and related metabolic disorders, arterial hypertension, vascular damage due to atherosclerotic process, cancer, chronic obstructive pulmonary disease, neurodegenerative diseases, chronic kidney disease, immune-mediated diseases) is increasing. There is incontrovertible evidence that regular physical activity contributes to the primary and secondary prevention of several chronic diseases and is associated with a reduced risk of premature death.
Methods: In this review the most prevalent chronic pathologic conditions are discussed, how regular exercise may provide benefits for prevention and/or treatment of these diseases and are graphically described by means of various figures the main biological mechanisms through which exercise exerts its beneficial effects known to date.
Results: Specific interventions aimed to implement physical activity levels of the general population are of certain efficacy both for primary and secondary prevention of the major chronic diseases and constitutes an excellent cost/effective tool to improve the health status of different categories of patients.
Conclusion: Exercise represents a unique case in which a single intervention is useful against a broad range of diseases and risk factors, this knowledge should lead to an ever-increasing use of this lifestyle change.
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Cite this article as:
Raimondo Di Domenico, Musiari Gaia, Miceli Giuseppe, Arnao Valentina and Pinto Antonio, Preventive and Therapeutic Role of Muscle Contraction Against Chronic Diseases, Current Pharmaceutical Design 2016; 22 (30) . https://dx.doi.org/10.2174/1381612822666160510125011
DOI https://dx.doi.org/10.2174/1381612822666160510125011 |
Print ISSN 1381-6128 |
Publisher Name Bentham Science Publisher |
Online ISSN 1873-4286 |
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