Investigation of Urolithiatic Activity of Prepared Polyherbal Formulations in Wister Rats

Title:Investigation of Urolithiatic Activity of Prepared Polyherbal Formulations in Wister Rats

Volume: 12 Issue: 2

Author(s): Prakash Rajak and Biman Bhuyan

Affiliation:

Keywords: Urolithiasis, herbal formulation, Bergenia ligulata, Didymocarpus pedicellata, Dolichos biflorus, Boerhaavia diffusa, Crataeva nurvala, Ocimum sanctum.

Abstract: Formulations were prepared containing Bergenia ligulata, Didymocarpus pedicellata, Dolichos biflorus, Boerhaavia diffusa, Crataeva nurvala and Ocimum sanctum in different ratios and coded as F1, F2 and F3. In vivo urolithiatic activities of the prepared formulations (i.e. F1:20, F1:40, F1:60, F2:20, F2:40, F2:60, F3:20, F3:40 and F3:60) were performed in rats using ethylene glycol induced urolithiasis model. It was observed that in comparison with the standard drug i.e. Cystone (30 mg/kg b wt.) the prepared formulation F3:60 (60 mg/kg b wt.) have shown significant antilithiatic activity.

Cite this article as:

Rajak Prakash and Bhuyan Biman, Investigation of Urolithiatic Activity of Prepared Polyherbal Formulations in Wister Rats, Current Bioactive Compounds 2016; 12 (2) . https://dx.doi.org/10.2174/157340721202160504221936