Abstract
Background: Cancer is one of the most serious illnesses of our civilization. Therefore, scientists of different disciplines try to find new treatment strategies and new chemical molecules which might be useful in a cancer treatment.
Objective: The goal of this work is to perform the most significant achievements in the area of chemotherapeutic treatment, published during the last two years.
Methods: We reviewed almost 80 contributions, searching for new molecules with anticancer activity and treatment strategies.
Results: We have presented tens of new anticancer molecules interacting with DNA or affecting cell cycle and new findings in this area. These compounds are chemically synthesized as well as are isolated from natural sources. The discovered molecules may induce cancer cells apoptosis, improve other cancer treatments, such as radiotherapy or reduce side effects of chemotherapy.
Conclusion: The review shows that the cancer battle is still in progress and the combined studies in different disciplines, devoted to this subject, are a rapidly expanding area.
Keywords: Anticancer molecules, cancer treatment, drugs, drug delivery, drug development, tumor, mechanisms of action.
Medicinal Chemistry
Title:New Hopes in Cancer Battle - A Review of New Molecules and Treatment Strategies
Volume: 12 Issue: 8
Author(s): Marika Turek, Magdalena Krzyczmonik and Piotr Balczewski
Affiliation:
Keywords: Anticancer molecules, cancer treatment, drugs, drug delivery, drug development, tumor, mechanisms of action.
Abstract: Background: Cancer is one of the most serious illnesses of our civilization. Therefore, scientists of different disciplines try to find new treatment strategies and new chemical molecules which might be useful in a cancer treatment.
Objective: The goal of this work is to perform the most significant achievements in the area of chemotherapeutic treatment, published during the last two years.
Methods: We reviewed almost 80 contributions, searching for new molecules with anticancer activity and treatment strategies.
Results: We have presented tens of new anticancer molecules interacting with DNA or affecting cell cycle and new findings in this area. These compounds are chemically synthesized as well as are isolated from natural sources. The discovered molecules may induce cancer cells apoptosis, improve other cancer treatments, such as radiotherapy or reduce side effects of chemotherapy.
Conclusion: The review shows that the cancer battle is still in progress and the combined studies in different disciplines, devoted to this subject, are a rapidly expanding area.
Export Options
About this article
Cite this article as:
Turek Marika, Krzyczmonik Magdalena and Balczewski Piotr, New Hopes in Cancer Battle - A Review of New Molecules and Treatment Strategies, Medicinal Chemistry 2016; 12 (8) . https://dx.doi.org/10.2174/1573406412666160502153700
DOI https://dx.doi.org/10.2174/1573406412666160502153700 |
Print ISSN 1573-4064 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6638 |
Call for Papers in Thematic Issues
Carbohydrates in Computational and Medicinal Chemistry
Carbohydrates are the most essential organic molecules and are involved in the maintenance of various physiological and metabolic processes in living organisms. Carbohydrate-based compounds have come to the attention of researchers because of their significant contributions to biological functions, such as cell development and cell proliferation, connections between several cells, ...read more
Recent Advances in the Medicinal Chemistry of Cancer
Scope of the Thematic Issue: Correlation between structure and function is one of the important aspects of the success of anti-cancer compounds associated with their structure-activity interactions, physiology, biochemical, molecular, and genetic processes. Overcoming these obstacles is key to obtaining further insights into developments in rational drug design, bioorganic chemistry, ...read more
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
Related Articles
-
Diagnoses of Gastrointestinal Cancers After Gastrointestinal Bleeding in Patients Receiving Clopidogrel or Warfarin
Current Drug Safety A Novel Method for Screening of Anti-Cancer Drugs: Availability of Screening in Acidic Medium
Recent Patents on Biomedical Engineering (Discontinued) Cholestasis During Pregnancy: Aetiopathogenesis, Foetal-Maternal Repercussions and Pharmacological Treatments
Current Women`s Health Reviews Validated RP-HPLC Method for the Simultaneous Analysis of Gemcitabine and LY-364947 in Liposomal Formulations
Current Drug Targets Strategies for the Design of Non-peptide CCK2 Receptor Agonist and Antagonist Ligands
Current Topics in Medicinal Chemistry Comparative Safety Assessment Study for Drospirenone Induced Gallbladder Diseases Using the Adverse Drug Reaction Database of USA, Europe, and Canada
Current Drug Safety New Molecular Targets of Anticancer Therapy – Current Status and Perspectives
Current Medicinal Chemistry Critical Functions of lncRNA DGCR5 in Cancers of the Digestive System
Current Pharmaceutical Design Portal Vein Embolization: A Preoperative Approach to Improve the Safety of Major Hepatic Resection
Current Medical Imaging Strategies for Overcoming Chemotherapy Resistance in Enterohepatic Tumours
Current Molecular Medicine Extranodal Marginal Zone B-Cell Lymphoma of Mucosa Associated Lymphoid Tissue Presenting as Multiple Pulmonary Lesions: Case Report and Review of the Literature
Current Respiratory Medicine Reviews Peptides Targeting Gap Junctional Structures
Current Pharmaceutical Design The Dynamics of the Hypothalamic-Pituitary-Ovarian Axis, ReproductivePerformance and Sexuality Following Bariatric Surgery
Current Women`s Health Reviews Looking out for Cancer Stem Cells’ Properties: The Value-Driving Role of CD44 for Personalized Medicines
Current Cancer Drug Targets The Biology of Cholecystokinin and Gastrin Peptides
Current Topics in Medicinal Chemistry Adiposity and the Gut - The Role of Gut Hormones
Current Nutrition & Food Science Long Term Prognosis in IgG4-Related Systemic Disease (ISD)
Current Immunology Reviews (Discontinued) Chronic Inflammation and Cancer: The Role of Endothelial Dysfunction and Vascular Inflammation
Current Pharmaceutical Design Jab1-siRNA Induces Cell Growth Inhibition and Cell Cycle Arrest in Gall Bladder Cancer Cells via Targeting Jab1 Signalosome
Anti-Cancer Agents in Medicinal Chemistry DNA Demethylation by TET Proteins: A Potential Therapeutic Target in Cancer
Epigenetic Diagnosis & Therapy (Discontinued)