Chitosan and propolis are natural substances that can be commonly found in the
environment. Chitosan is one of the several cationic polysaccharides found in nature. It is a natural
biopolymer transformed from chitin which is a product of crustacean shells. Propolis is produced by
honeybees through mixing the secretions of their hypopharyngeal glands with the digested product of
resins collected from plants. Due to their excellent chemical and biological properties, chitosan and
propolis arouse keen interest in dental science, including endodontics. There are various possibilities for
applying propolis and chitosan based medicaments in endodontic treatment of root canals, and what is
particularly emphasized is their potential effectiveness against resistant microorganisms such as
E. faecalis and C. albicans, as well as biocompatible to the periapical tissues in comparison with the
most commonly used agents. They aim at microflora which is difficult to eliminate, and their medicinal
properties, including anti-inflammatory, antifungal and antiseptic properties, make them suitable for use
in endodontic treatment. Due to the potential side effects of commonly used synthetic drugs and other
safety related reasons, natural alternatives for endodontic usage are continuously explored and tested.
The paper presents the possibilities of applying propolis and chitosan in endodontic treatment on the
basis of chosen articles published in recent years.
Keywords: Chitosan, chitosan in endodontic treatment, endodontics, natural products in endodontic treatment, natural
substances in dentistry, propolis, propolis in endodontic treatment.
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