Lipid Nanoparticles and their Application in Nanomedicine

Author(s): Mehdi Rajabi, Shaker A. Mousa.

Journal Name: Current Pharmaceutical Biotechnology

Volume 17 , Issue 8 , 2016

Abstract:

In recent years many different nanotechnology platforms have been developed for both diagnostics and cancer therapy. Researchers have been attracted to use lipid-based nanoparticles with particle size approximately 100 nm as a new pharmaceutical delivery system or pharmaceutical formulation that can be assembled from different types of lipid or other chemical components in order to overcome biological barriers. This mini-review highlights the recently published studies in the development of lipid-based nanoparticles as appropriate vehicles in cancer diagnosis and therapy with focus on their chemical structure, formulation recipes, stability, drug encapsulation, and other factors related to their formulation.

Keywords: Drug delivery, lipid, lipid-based nanoparticles (LNPs), liposome, solid lipid nanoparticle (SLN), nanotechnology.

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Article Details

VOLUME: 17
ISSUE: 8
Year: 2016
Page: [662 - 672]
Pages: 11
DOI: 10.2174/1389201017666160415155457
Price: $58

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