Recent Advancement in Natural Hyaluronidase Inhibitors

Author(s): Luciana Scotti, Rajeev Kumar Singla, Hamilton Mitsugu Ishiki, Francisco Jaime B. Mendonca, Marcelo Sobral da Silva, José Maria Barbosa Filho, Marcus Tullius Scotti.

Journal Name: Current Topics in Medicinal Chemistry

Volume 16 , Issue 23 , 2016

Abstract:

The use of natural products for the treatment of disease is one of the oldest cultures exists. Currently, the research of new drugs using natural products shows a poorly explored biodiversity and a great interest of marketing. The enzymatic inhibition by some natural products is investigated among these is the inhibition of hyaluronidase and the consequent reduction of the degradation of hyaluronic acid. So there is a reduction of inflammation and angiogenesis. This study reports the main natural species studied in inhibiting human hyaluronidase that can be the subject of future research for new drugs.

Keywords: Enzyme, inhibition, hyaluronidase, natural products, inflammation, angiogenesis.

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Article Details

VOLUME: 16
ISSUE: 23
Year: 2016
Page: [2525 - 2531]
Pages: 7
DOI: 10.2174/1568026616666160414123857
Price: $58

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