Oxazole: A Promising Building Block for the Development of Potent Antitumor Agents

Author(s): Hua Zhou, Jiang-Qun Cheng, Zhi-Sen Wang, Fei-Hu Chen, Xin-Hua Liu.

Journal Name: Current Topics in Medicinal Chemistry

Volume 16 , Issue 30 , 2016

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Abstract:

Oxazole derivatives are found to have a variety of biological activities. A large number of studies have revealed their outstanding anticancer activities. Here we review four different types of oxazole derivatives with anticancer potential reported over the last ten years. We focus our discussion on their activity, selectivity in different cancer cell lines, mechanisms of action, and their structural evolution.

Keywords: Activity, Annulated oxazole, Anticancer inhibitors, Oxazole, Oxazolidinone, Macrocyclic.

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Article Details

VOLUME: 16
ISSUE: 30
Year: 2016
Page: [3582 - 3589]
Pages: 8
DOI: 10.2174/1568026616666160414122521
Price: $58

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