Recent Advances in the Synthesis of 1,3-Azoles

Author(s): Nadale K. Downer-Riley, Yvette A. Jackson.

Journal Name: Current Topics in Medicinal Chemistry

Volume 16 , Issue 30 , 2016

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Abstract:

The 1,3-azole motif is a common and integral feature of many clinical drugs. Due to their wide-ranging applications, the development of 1,3-azoles as therapeutic agents is an ongoing focus of medicinal chemists. This review highlights the recent approaches towards the assembly of 1,3-oxazole, 1,3-thiazole and 1,3-imidazole motifs.

Keywords: 1, 3-Azoles, Imidazole, Oxazole, Synthesis, Therapeutic agent, Thiazole.

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Article Details

VOLUME: 16
ISSUE: 30
Year: 2016
Page: [3617 - 3626]
Pages: 10
DOI: 10.2174/1568026616666160414122349
Price: $58

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