Cardiovascular disease (CVD) remains a major cause of death and disability worldwide, thus preventing
and inhibiting CVD remains a health priority. Several lines of pharmacological interventions have not met with
great success, thus inhibition of novel cellular stress pathways could be a novel therapeutic avenue to treat CVD.
This review will focus on homocysteine and endoplasmic reticulum stress linked to mitochondria function, and
possible therapeutic avenues for treatment.
Keywords: Endoplasmic reticulum stress, endothelial function, homocysteine, atherosclerosis, taurine, Nox.
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