Anti-Psoriasis Agents from Natural Plant Sources

Author(s): Marco Bonesi, Monica Rosa Loizzo, Eugenio Provenzano, Francesco Menichini, Rosa Tundis.

Journal Name: Current Medicinal Chemistry

Volume 23 , Issue 12 , 2016

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Psoriasis is a chronic inflammatory immune-mediated skin disease. It affects most races, does not have any sexual predilections and can manifest at any age of life. Psoriasis is more frequent in certain racial groups and geographical areas. For these reasons, both genetic and environmental factors could be considered. In this review, we discuss promising natural compounds, their molecular targets and mechanisms, which may help the further design of new anti-psoriasis agents. Literature documents the widespread use of herbal remedies worldwide, and the presence of some phytochemicals supports the efficacy of some botanical treatments. The research on natural products has greatly contributed to the progress in the treatment of skin diseases such as psoriasis and many of these compounds are now being used. Understanding the mechanism of these molecules will contribute to the development of more specific preventive strategies for the treatment of psoriasis.

Keywords: Psoriasis, skin, botanicals, medicinal plants, mechanism of action.

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Article Details

Year: 2016
Page: [1250 - 1267]
Pages: 18
DOI: 10.2174/0929867323666160321121819
Price: $58

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PDF: 37
PRC: 1