The Potential Application of Biomaterials in Cardiac Stem Cell Therapy

Author(s): Raja Ghazanfar Ali Sahito, Poornima Sureshkumar, Isaia Sotiriadou, Sureshkumar Perumal Srinivasan, Davood Sabour, Jürgen Hescheler, Kurt Pfannkuche, Agapios Sachinidis.

Journal Name: Current Medicinal Chemistry

Volume 23 , Issue 6 , 2016

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Abstract:

Biomaterials play a vital role in the field of regenerative medicine and tissue engineering. To date, a large number of biomaterials have been used in cardiovascular research and application. Recently, biomaterials have held a lot of promise in cardiac stem cell therapy. They are used in cardiac tissue engineering to form scaffolds for cellular transplantation, promote angiogenesis, enhance transplanted cell engraftment or influence cell migration. The science of biomaterial designing has evolved to an extent where they can be designed to mimic the microenvironment of a cardiac tissue in vivo and contribute in deciding the fate of transplanted stem cells and induce cardiac lineage oriented stem cell differentiation. In this review, we focus on biomaterials used in cardiovascular stem cell research, tissue engineering and regenerative medicine and conclude with an outlook on future impacts of biomaterial in medical sciences.

Keywords: Scaffold biomaterials, polymers, stem cells, tissue engineering, regenerative medicine, therapeutics.

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Article Details

VOLUME: 23
ISSUE: 6
Year: 2016
Page: [589 - 602]
Pages: 14
DOI: 10.2174/092986732306160303151041
Price: $58

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