Abstract
Background: Benzodiazaphosphorines have many biological activities such as fungicidal and antitumor. In this work we are interested to synthesize them in order to test their activities in future work. The probable mechanism of obtained benzodiazaphosphorines is discussed.
Methods: The obtained benzodiazaphosphorines were characterized using FT-IR, NMR 1H and 13C spectroscopy and elemental analysis.
Results: A series of new benzodiazaphosphorines products synthesized were purified by crystallization and obtained with good yields.
Conclusion: In this paper we have synthesized a series of benzodiazaphosphorine and benzodiazaphosphorine sulfide which are identified using FT-IR, NMR spectroscopy and elemental analysis. The prepared compounds will be subsequently studied in order to tested their biological activities
Keywords: 1, 3, 2-benzodiazaphosphorine, 1, 3, 2-benzodiazaphosphorine-2-sulfide, 2-amino-benzamidine, sulfur, tris (dimethyl amino) phosphine.
Graphical Abstract
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