Synthetic Routes to Spirocyclic Pyridazines, Partially-Saturated Pyridazines and Their Condensed Derivatives

Author(s): Amr M. Abdelmoniem, Ismail A. Abdelhamid.

Journal Name: Current Organic Chemistry

Volume 20 , Issue 14 , 2016

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Abstract:

Different synthetic strategies to 4,4-disubstituted pyridazines and condensed pyridazines with a special reference to the synthetic routes to their spiro analogues are comprehensively outlined in this review.

Keywords: Spirocyclic pyridazines, partially-saturated pyridazines, synthesis, retro- Diels-Alder, 1, 3-dipolar cycloaddition, Aza-Michael addition, nucleophilic reactions.

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Article Details

VOLUME: 20
ISSUE: 14
Year: 2016
Page: [1512 - 1546]
Pages: 35
DOI: 10.2174/1385272820666160216224951
Price: $58

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