Biological Properties of Plant-Derived Alkylresorcinols: Mini-Review

Author(s): Ângelo Luís, Fernanda Domingues, Ana Paula Duarte.

Journal Name: Mini-Reviews in Medicinal Chemistry

Volume 16 , Issue 11 , 2016

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Abstract:

Alkylresorcinols are compounds which belong to the family of phenolic lipids, and are usually found in numerous biological species. In the particular case of higher plants, alkylresorcinols have been found in various counterparts with chains of thirteen to twenty-seven carbon atoms containing several saturations. Due to the demonstrated antimicrobial properties of many naturally occurring members of the alkylresorcinols family, it is possible to conclude that these compounds act as defensive agents in plants. Previous studies led to the isolation and identification of 5-alkylresorcinols that cleave DNA. Additionally, in the literature, there are several other biological effects attributed to some resorcinol derivatives, namely, cytotoxic, anticarcinogenic, antiproliferative, antileishmanial and antioxidant properties. This mini-review intends to outline the biological activities of the most relevant alkylresorcinols isolated from plants and to propose future directions for subsequent studies regarding the effective biological effects of this class of compounds.

Keywords: Alkylresorcinols, biological properties, phenolic lipids, resorcinols.

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Article Details

VOLUME: 16
ISSUE: 11
Year: 2016
Page: [851 - 854]
Pages: 4
DOI: 10.2174/1389557516666160211121437
Price: $58

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