The Suicidal Risks and Treatments, Seek Medications from Multi-disciplinary

Author(s): Da-Yong Lu, Peng-Peng Zhu, Ting-Ren Lu, Jin-Yu Che.

Journal Name: Central Nervous System Agents in Medicinal Chemistry
(Formerly Current Medicinal Chemistry - Central Nervous System Agents)

Volume 16 , Issue 3 , 2016

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Abstract:

Suicide events and episodes are serious human psychiatric disorders affected by a great number of different environmental/economic factors, early trauma/abuse, human bad living habits, human genomic properties and drug intervention decisions. In order to improve antidepressant therapeutics in clinics, the relationships between efficacy and toxicities of antidepressants have to be considered fundamentally. Since the occurrences and risks of suicidal events or episodes come from interplay between insiders (chemical/genomic/bioinformatics factors) and outsiders (economic/social/ previous trauma conditions and so on), new perspectives and scientific studies must be implemented for revealing these interrelated factors step-by-step and updating therapeutics in human beings. New paradigms and clinical strategies –joint-expert groups and clinical practices (a psychiatrist with other field specialists) should be established for individual patients in future. Thus can some improvements in clinical trials be achieved in a long run?

Keywords: Economic conditions, environmental factors, human genome, medicinal chemistry, neural toxicity, Psychiatric disorders.

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Article Details

VOLUME: 16
ISSUE: 3
Year: 2016
Page: [231 - 239]
Pages: 9
DOI: 10.2174/1871524916666160210142734
Price: $58

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