Progress of Synthesis and Separation of Regioisomerically Pure 5(6)-Substituted Rhodamine

Author(s): Mei Fu, Xiaowei Zhang, Jun Wang, Hongwei Chen, Yong Gao.

Journal Name: Current Organic Chemistry

Volume 20 , Issue 15 , 2016

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Abstract:

Regioisomerically pure 5(6)-substituted rhodamine is an outstanding molecular platform for functional probes and a very useful material for fluorescent labels. However, 5(6)-substituted rhodamine is difficult to be synthesized by general methods, which limits the application of the dye. This review highlights the progress regarding the methods for the synthesis and separation of regioisomerically pure 5(6)-substituted rhodamine, which are categorized by the four different protocols for acquiring 5(6)-substituted rhodamine. The advantages and disadvantages of each protocol are also discussed.

Keywords: Regioisomerically pure, substituted rhodamine, separation, synthesis.

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Article Details

VOLUME: 20
ISSUE: 15
Year: 2016
Page: [1584 - 1590]
Pages: 7
DOI: 10.2174/1385272820666160202004127
Price: $58

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