Frontiers in Medicinal Chemistry

Volume: 8

Indexed in: Book Citation Index, Science (BKCI-S), Web of Science, BIOSIS Previews, EMBASE, Chemical Abstracts, EBSCO., Ulrich's Periodicals

Frontiers in Medicinal Chemistry is an Ebook series devoted to the review of areas of important topical interest to medicinal chemists and others in allied disciplines. Frontiers in Medicinal ...
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Calixarenes in Biotechnology and Bio-Medical Research

Pp. 206-301 (96)

Roman V. Rodik, Vyacheslav I. Boyko and Vitaly I. Kalchenko

Abstract

Application of calixarene derivatives in biotechnology and bio-medical researches is reviewed in this article. Results on antiviral, bactericidal, antithrombothic, antituberculosis, anticancer activities of modified calixarenes are presented. Transfection ability, specific protein complexation, enzyme mimic, membranotropic properties and toxicity of modified calixarenes are described.

Keywords:

Alkaline phosphatase, anticancer, anticoagulant and antithrombotic, antituberculosis activity, antiviral, bactericidal, calixarenes, chloride channel, enzyme mimic, fungicidal, magnetic resonance imaging, protein complexation, protein tyrosine phosphatase, sodium-potassium pump, toxicity, transfection.

Affiliation:

Institute of Organic Chemistry, National Academy of Sciences of Ukraine, Murmanska Str., 5 02660, Kyiv-94, Ukraine.