RBM15 Functions in Blood Diseases

Author(s): Mengyu Hu, Yuxia Yang, Zhi Ji, Jianyuan Luo.

Journal Name: Current Cancer Drug Targets

Volume 16 , Issue 7 , 2016

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Abstract:

RBM15, an RNA-binding protein, plays important roles in the growth and apoptosis of cells, especially blood cells through regulating multiple signal pathways such as Notch and Wnt. An increasing body of evidence has suggested that RBM15 may play a key function on the development of various blood diseases, such as acute/chronic myeloid leukemia and kaposi′s sarcoma. In this review, we will focus on the progress of the association between RBM15 and its related blood diseases.

Keywords: RBM15, blood diseases, function, mechanism.

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Article Details

VOLUME: 16
ISSUE: 7
Year: 2016
Page: [579 - 585]
Pages: 7
DOI: 10.2174/1568009616666160112105706
Price: $58

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