Updated Report on Synthesis and Biological Properties of Oxadiazine-Based Heterocyclic Derivatives
Pp. 107-143 (37)
Xiufang Cao and Shaoyong Ke
Oxadiazine scaffold-based compounds are undoubtedly an important class of
heterocyclic derivatives, which always present diverse bioactivities including
cardiovascular, antitumor, antiviral, anti-leishmanial, antibacterial, antimicrobial,
monoamine oxidase inhibition, acricidal, insecticidal, plant-growth regulating activities
and chitin biosynthesis inhibitions. With the development of organic synthesis, versatile
features of oxadiazine ring have emerged, so here we have reviewed the recent
advances of oxadiazine-based heterocyclic derivatives mainly including preparation,
transformation and biological properties, and this report is also an updated version of
our previous review with modifications.
Oxadiazine, oxadiazinone, heterocyclic scaffold, synthetic method,
pharmaceutical activity, pesticidal activity, biological application.
National Biopesticide Engineering Research Center, Hubei Academy of Agricultural Sciences, Wuhan 430064, People`s Republic of China.