Age-Related Sleep Changes and its Implication in Neurodegenerative Diseases

Author(s): Elena A. Lyashenko , Michael G. Poluektov , Oleg S. Levin , Polina V. Pchelina .

Journal Name: Current Aging Science

Volume 9 , Issue 1 , 2016

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Abstract:

In the article authors discuss the current data on sleep changes with aging focusing on the influence of age-related degenerative changes in orexin-containing and pacemaker brain areas. Pathophysiological mechanisms of sleep disturbances in Parkinson’s and Alzheimer’s diseases have much in common with normal age neurophysiological changes. Maintenance of the sleep-promoting systems function could positively modify the course of these diseases.

Keywords: Age, Alzheimer’s disease, Parkinson’s disease, sleep, orexins, sleep disorders.

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Article Details

VOLUME: 9
ISSUE: 1
Year: 2016
Page: [26 - 33]
Pages: 8
DOI: 10.2174/1874609809666151130220219

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