Withania somnifera is an important medicinal herb that has been widely used for the treatment of different
clinical conditions. The overall medicinal properties of Withania somnifera make it a viable therapeutic agent
for addressing anxiety, cancer, microbial infection, immunomodulation, and neurodegenerative disorders. Biochemical
constituents of Withania somnifera like withanolideA, withanolide D, withaferin A and withaniamides
play an important role in its pharmacological properties. Proteins like Withania somnifera glycoprotein and withania
lectin like-protein possess potent therapeutic properties like antimicrobial, anti-snake venom poison and antimicrobial.
In this review, we have tried to present different pharmacological properties associated with different extract
preparations, phytochemical constituents and protein component of Withania somnifera. Future insights in this
direction have also been highlighted.
Keywords: Immunomodulation, neurodegenerative disorders, anti-microbial, withanolides, withaferin, glycoprotein.
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