Recent studies have shown that visit-to-visit blood pressure (BP) variability was emerging as an
independent risk factor for stroke. Although the mechanism is not fully understood, artery remodeling would be
closely associated with the relationship between visit-to-visit BP variability and stroke. In addition, the class of
antihypertensive agents is suggested to be an important determinant of visit-to-visit BP variability. This review article
summarizes the recent literature on these topics. In the elderly hypertensives, strict BP control using calcium
channel blockade would play a crucial role to prevent stroke via reducing the visit-to-visit BP variability.
Keywords: Artery remodeling and stroke, classes of antihypertensive agents, hypertension, visit-to-visit blood
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