Oxidative stress and Parkinson’s disease: New hopes in treatment with herbal antioxidants

Author(s): Amir Sarrafchi, Mahmoud Bahmani, Hedayatollah Shirzad, Mahmoud Rafieian-Kopaei.

Journal Name: Current Pharmaceutical Design

Volume 22 , Issue 2 , 2016

Abstract:

Parkinson's disease (PD) is a neurodegenerative disorder due to dopamine deficit in substatia nigra. PD is mainly a sporadic disease with unestablished etiology. However, exposure to environmental toxins, head trauma, inflammation, and free radicals are potential reasons. Recently, the role of oxidative stress in neurological abnormalities, including PD, has been particularly addressed. Antioxidant remedies, particularly herbal antioxidants, have revealed new perspectives of research and therapy as possible preventive and therapeutic approaches for PD. In this paper, we reviewed the recently published papers on the effects of herbal medicines on PD alongside the pathogenesis of PD with regard to oxidative stress.

Keywords: Antioxidant, degenerative disorder, herbal medicines, medicinal plants, oxidative stress, Parkinson's disease.

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Article Details

VOLUME: 22
ISSUE: 2
Year: 2016
Page: [238 - 246]
Pages: 9
DOI: 10.2174/1381612822666151112151653
Price: $58

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