The relatively simple peptides assembled on the templates are excellent mimic of complex
conformational and functional defined binding sites of proteins. The main benefit of experiments with
artificial receptors arises from the relative simplicity of the interacting host-guest system allowing the
understanding of the rules controlling the model process of the molecular recognition. Efficient modification
of molecular receptors by using rational design of their structure or combinatorial methods is
crucial for verification of any hypothesis concerning the binding forces or enhancing the binding properties.
This approach is presenting promising strategy for understanding mode of action and the control
of biological functions of proteins, for designing new pharmaceutically active compounds, new
tools for medical diagnostic and molecular sensing.
Keywords: artificial protein mimics, cellulose, combinatorial chemistry, molecular receptor, protein binding, host-guest interactions.
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