The incidence of gastric cancer is third most prevalent among all malignant tumors in
China. The conventional therapies for advanced gastric cancer are futile. Targeted gene therapy has
become a promising alternative approach. Mesenchymal stem cells (MSCs) can be used as potential
cellular vehicles for cancer therapy in vivo. This review will summarize the published data about the
application of MSC-based targeted therapy for gastric cancer, and discuss some of the challenges associated
with this method.
Keywords: Challenges, conventional therapies, gastric cancer, mesenchymal stem cells, targeted gene therapy, vehicle.
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