Application of Mesenchymal Stem Cells in the Targeted Gene Therapy for Gastric Cancer

Author(s): Ya-Li Zhou, Yu-Min Li, Wen-Ting He.

Journal Name: Current Stem Cell Research & Therapy

Volume 11 , Issue 5 , 2016

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Abstract:

The incidence of gastric cancer is third most prevalent among all malignant tumors in China. The conventional therapies for advanced gastric cancer are futile. Targeted gene therapy has become a promising alternative approach. Mesenchymal stem cells (MSCs) can be used as potential cellular vehicles for cancer therapy in vivo. This review will summarize the published data about the application of MSC-based targeted therapy for gastric cancer, and discuss some of the challenges associated with this method.

Keywords: Challenges, conventional therapies, gastric cancer, mesenchymal stem cells, targeted gene therapy, vehicle.

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Article Details

VOLUME: 11
ISSUE: 5
Year: 2016
Page: [434 - 439]
Pages: 6
DOI: 10.2174/1574888X10666151026113818
Price: $58

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