Urinary bladder carcinoma is estimated to be the ninth most common cause of
cancer worldwide. The treatment of bladder carcinoma is an area of active research owing
to lack of evidence of any treatment modality. Traditionally surgery, cystectomy, was considered
the cornerstone of therapy. However, the morbidity of such approach has paved for
bladder preservation approach with radiation in combination with chemotherapy. The use of
transurethral resection of bladder tumor along with radiation and chemotherapy helps patients
to have a functional bladder without compromising survival. Adjuvant radiation is an
underutilized treatment modality. In the present era availability of sophisticated radiation
technique allows delivery of radiation without increasing toxicity. Hence, adjuvant radiation may be used for
patients with R1 resection and lymph node positive disease alone or in combination with chemotherapy. Radiation
also appears a valuable treatment option for palliation in bladder tumor. We herein intend to review
the present place of radiation in the management of transitional cell carcinoma of urinary bladder.
Keywords: Bladder carcinoma, chemo-radiotherapy, locally advanced.
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