Metabolic acidosis is one of the common manifestations of Isoniazid toxicity but rare with
normally used doses of the drug. Among anti tubercular drugs, rifampicin, streptomycin and
capreomycin are commonly implicated in renal injury. Here we report the first case of metabolic
acidosis and renal injury caused by isoniazid at normal prescribed dose.
Keywords: Isoniazid, metabolic acidosis, renal dysfunction.
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