Bisindolylmethane and its derivatives are pharmacologically active
and applicable in the field of pharmaceutical chemistry. Bisindolylmethanes
have a variety of biological activities such as antihyperglycemic, antiinflammatory,
antibacterial, anticancer, and antileishmanial activities, including
enzyme inhibition activity. They play a crucial role in many diseases especially anticancer activity. Modifying
their structure had proven to be useful in the search of new therapeutic agents. Extensive research carried
out on bisindolylmethane and its derivatives shows that they are pharmacologically significant. The present
review focuses on the pharmacological profile of bisindolylmethane derivatives. This review includes the
current literature with an update of research findings as well as the perspectives that they hold for future research.
Keywords: Anticancer, anti-inflammation, bisindolylmethane, heterocycles, indole, pharmacological activities.
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