The Use of Mathematical Modelling for Improving the Tissue Engineering of Organs and Stem Cell Therapy

Author(s): Greg Lemon, Sebastian Sjoqvist, Mei Ling Lim, Neus Feliu, Alexandra B. Firsova, Risul Amin, Ylva Gustafsson, Annika Stuewer, Elena Gubareva, Johannes Haag, Philipp Jungebluth, Paolo Macchiarini.

Journal Name: Current Stem Cell Research & Therapy

Volume 11 , Issue 8 , 2016


Regenerative medicine is a multidisciplinary field where continued progress relies on the incorporation of a diverse set of technologies from a wide range of disciplines within medicine, science and engineering. This review describes how one such technique, mathematical modelling, can be utilised to improve the tissue engineering of organs and stem cell therapy. Several case studies, taken from research carried out by our group, ACTREM, demonstrate the utility of mechanistic mathematical models to help aid the design and optimisation of protocols in regenerative medicine.

Keywords: Regenerative medicine, tissue engineering, stem cell therapy, stem cells, mathematical modelling, computational modelling.

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Article Details

Year: 2016
Page: [666 - 675]
Pages: 10
DOI: 10.2174/1574888X10666151001115942
Price: $58

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