Insights in Nanoparticle-Bacterium Interactions: New Frontiers to Bypass Bacterial Resistance to Antibiotics

Author(s): Roudayna Diab , Bahman Khameneh , Olivier Joubert , Raphael Duval .

Journal Name: Current Pharmaceutical Design

Volume 21 , Issue 28 , 2015

Abstract:

Nanotechnology has been revealed as a fundamental approach for antibiotics delivery. In this paper, recent findings demonstrating the superiority of nanocarried-antibiotics over “naked” ones and the ways by which nanoparticles can help to overwhelm bacterial drug resistance are reviewed. The second part of this paper sheds light on nanoparticle-bacterium interaction patterns. Finally, key factors affecting the effectiveness of nanoparticles interactions with bacteria are discussed.

Keywords: Antibiotic, controlled-release, liposome, nanoparticle, resistance, targeting.

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Article Details

VOLUME: 21
ISSUE: 28
Year: 2015
Page: [4095 - 4105]
Pages: 11
DOI: 10.2174/138161282128150922175445
Price: $58

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