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Current Pharmaceutical Design

Editor-in-Chief

ISSN (Print): 1381-6128
ISSN (Online): 1873-4286

Insights in Nanoparticle-Bacterium Interactions: New Frontiers to Bypass Bacterial Resistance to Antibiotics

Author(s): Roudayna Diab, Bahman Khameneh, Olivier Joubert and Raphael Duval

Volume 21, Issue 28, 2015

Page: [4095 - 4105] Pages: 11

DOI: 10.2174/138161282128150922175445

Price: $65

Abstract

Nanotechnology has been revealed as a fundamental approach for antibiotics delivery. In this paper, recent findings demonstrating the superiority of nanocarried-antibiotics over “naked” ones and the ways by which nanoparticles can help to overwhelm bacterial drug resistance are reviewed. The second part of this paper sheds light on nanoparticle-bacterium interaction patterns. Finally, key factors affecting the effectiveness of nanoparticles interactions with bacteria are discussed.

Keywords: Antibiotic, controlled-release, liposome, nanoparticle, resistance, targeting.


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