Background: Juvenile Idiopathic Arthritis is the most common chronic, autoimmune, inflammatory
joint disease affecting children under 16 years of age. Children with juvenile idiopathic
arthritis may present with severe lower limb joint disability and dysfunction. The evidence base for
treating lower limb problems in juvenile idiopathic arthritis is growing, however is currently uncoordinated
and difficult for clinicians to access. This paper reports a protocol to systematically review the
evidence for physical and mechanical interventions for lower limb problems in juvenile idiopathic arthritis.
Methods/Design: The following electronic databases will be searched for eligible studies:
MEDLINE, EMBASE, Cochrane Central Registar of Controlled Trials, PUBMED and CINAHL. Randomised control trials
and quasi randomised control trials of physical and mechanical interventions for lower limb problems in children with
juvenile idiopathic arthritis will be included. Two authors will independently screen studies for eligibility for inclusion
and assess the risk of bias. One author will extract and analyse statistical data, which will be checked by a second author.
Discussion: This systematic review aims to establish a best-practice pathway of non-invasive and non-drug interventions
for lower limb complications of juvenile idiopathic arthritis and to highlight the areas of greatest need for future research.
Keywords: Children, foot orthoses, foot, juvenile idiopathic arthritis, lower limb.
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