Recent Advances in Anticancer Chemotherapeutics based upon Azepine Scaffold

Author(s): Sarbjit Singh, Jail Goo, Veeraswamy Gajulapati, Tong-Shin Chang, Kyeong Lee, Yongseok Choi.

Journal Name: Anti-Cancer Agents in Medicinal Chemistry

Volume 16 , Issue 5 , 2016

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Abstract:

In the recent few years, the emergence of heterocyclic ring-containing anti-cancer agents has gained a great deal of attention among medicinal chemists. Among these, azepine-based compounds are particularly becoming attractive recently. In this Focus Review, we highlight the recent advancements in the development of azepine-based anti-cancer compounds since the year 2000.

Keywords: Anticancer agents, azepane scaffold, chemotherapeutics, histone deacetylases, kinase inhibitors, tubulin inhibitors, phototherapeutic agents, hormone modulators.

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Article Details

VOLUME: 16
ISSUE: 5
Year: 2016
Page: [539 - 557]
Pages: 19
DOI: 10.2174/1871520615666150916091750
Price: $58

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